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科学研究

科研动态

2012年

时间:2018年04月18日 访问次数:
1、Tan Yi, Li XK, Prabhu SD., Brittian KR., Chen Q, Yin X, McClain CJ, Zhou ZX, Cai L*: Angiotensin II Plays a Critical Role in Alcohol-Induced Cardiac Nitrative Damage, Cell Death, Remodeling, and Cardiomyopathy in a Protein Kinase C/Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Dependent Manner. Journal of the American College of Cardiology. 2012, 17, 59(16): 1477-1486. (IF=16.503)
2、Zhang L, Lu CT, Li WF, Cheng JG, Tian XQ*, Zhao YZ, Li X, Lv HF, Li XK: Physical characterization and cellular uptake of propylene glycol liposomes in vitro. Drug Development and Industrial Pharmacy. 2012, 38(3): 365-371. (IF=2.101) 
3、Zhang MJ, Jiang XB, Su ZJ, Lin JC, Xiang Q, Yang Z, Huang YD*, Li XK: Large-scale expression, purification, and glucose uptake activity of recombinant human FGF21 in Escherichia coli. Applied Microbiology and Biotechnology. 2012, 93(2): 613-621. (IF=3.337)
4、Zhang HY, Jia JM, Cheng JG, Ye FQ, Li XK, Gao HC*: 1H-NMR-based metabonomics study on serum of renal interstitial fibrosis rats induced by unilateral ureteral obstruction. Molecular Biosystems. 2012, 8(2): 595-601. (IF=3.21) 
5、Sun Y, Teng I, Huo RD, Rosenfeld MG., Olson LE., Li XK, Li X*: Asymmetric requirement of surface epithelial beta-catenin during the upper and lower jaw development. Developmental Dynamics. 2012, 241(4): 663-674. (IF=2.376)
6、Zhang X, Zhang HQ, Zhu GH, Wang YH, Yu XC, Zhu XB, Liang G, Xiao J*, Li XK: A novel mono-carbonyl analogue of curcumin induces apoptosis in ovarian carcinoma cells via endoplasmic reticulum stress and reactive oxygen species production. Molecular Medicine Reports. 2012, 5(3): 739-744. (IF=1.554)
7、Cong WT, You WJ, Chen M, Ling J, Zhu ZX, Choi J, Jin LT*, Li XK: Negative visualization of DNA in agarose gel by eosin Y and its related mechanism. Analyst. 2012, 137(6): 1466-1472. (IF=4.107)
8、Yang CF*, Jin CL, Li XK, Wang F, McKeehan WL, Luo YD. Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB. Plos One, 2012, 7(3): e33870. (IF=3.234)
9、Wang Y, Yu C, Pan Y, Yang X, Huang Y, Feng Z, Li XK, Yang S, Liang G*. A Novel Synthetic Mono-Carbonyl Analogue of Curcumin, A13, Exhibits Anti-Inflammatory Effects In vivo by Inhibition of Inflammatory Mediators. Inflammation, 2012, 35(2): 594-604. (IF=2.208)
10、Zhu ZX, Cong WT, Ni MW, Wang X, Ma WD, Ye WJ, Jin LT*, Li XK. An improved silver stain for the visualization of lipopolysaccharides on polyacrylamide gels. Electrophoresis, 2012, 33(7): 1220-1223. (IF=3.028)
11、Li H, Dong Y, Yang J, Liu X, Wang Y, Yao N, Guan L, Wang N, Wu J, Li XK*: De Novo Transcriptome of Safflower and the Identification of Putative Genes for Oleosin and the Biosynthesis of Flavonoids. Plos One. 2012, 7(2). (IF=3.234)
12、Gao H*, Dong B, Jia J, Zhu H, Diao C, Yan Z, Huang Y, Li XK: Application of ex vivo H-1 NMR metabonomics to the characterization and possible detection of renal cell carcinoma metastases. Journal of Cancer Research and Clinical Oncology. 2012, 138(5): 753-761. (IF=3.081)
13、Zhu ZX, Cong WT, Zhou X, Chen M, Choi JK, Jin LT*, Li XK: Negative staining of lipopolysaccharides on polyacrylamide gels by using eosin B. Analytical Biochemistry. 2012, 426(1): 1-3. (IF=2.219)
14、Li Q, Gao S, Yu Y, Wang W, Chen X, Wang R, Li T, Wang C, Li XK, Wu X*: A novel bFGF antagonist peptide inhibits breast cancer cell growth. Molecular Medicine Reports. 2012, 6(1): 210-214. (IF=1.554)
15、Ye D, Li FY, Lam KS, Li H, Jia W, Wang Y, Man K, Lo CM, Li XK, Xu AM*: Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. Gut. 2012, 61(7): 1058-1067. (IF=14.66) 
16、Liu Q, Sun Y, Su W, Yang J, Liu X, Wang Y, Wang F, Li H*, Li XK*: Species-specific size expansion and molecular evolution of the oleosins in angiosperms. Gene. 2012, 509(2): 247-257. (IF=2.138) 
17、Zhao YZ, Lu CT, Li XK, Tang QQ, Tian XQ*, Zhao YP, Zhang Y, Tian JL, Yang W, Ge S, Nair CK, Shen X. Improving the cardio protective effect of aFGF in ischemic myocardium with ultrasound-mediated cavitation of heparin modified microbubbles. preliminary experiment. J Drug Target. 2012, 20(7): 623-631. (IF=2.741) 
18、Zhao YZ, Dai DD, Lu CT, Lv HF, Zhang Y, Li X, Li WF*, Wu Y, Jiang L, Li XK, Huang PT, Chen LJ, Lin M: Using acoustic cavitation to enhance chemotherapy of DOX liposomes: experiment in vitro and in vivo. Drug Dev Ind Pharm. 2012, 38(9): 1090-1098. (IF=2.101) 
19、Zhao YZ, Li X, Lu CT*, Xu YY, Lv HF, Dai DD, Zhang L, Sun CZ, Yang W, Li XK, Zhao YP, Fu HX, Cai L, Lin M, Chen LJ, Zhang M: Experiment on the feasibility of using modified gelatin nanoparticles as insulin pulmonary administration system for diabetes therapy. Acta Diabetol. 2012, 49(4): 315-325. (IF=2.399) 
20、Liu Y, Wang C, Wang Y, Ma Z, Xiao J, McClain C, Li XK, Feng W*: Cobalt chloride decreases fibroblast growth factor-21 expression dependent on oxidative stress but not hypoxia-inducible factor in Caco-2 cells. Toxicol Appl Pharmacol. 2012, 264(2): 212-221. (IF=3.705)
21、Liang G*, Liu Z, Wu J, Cai Y, Li XK*: Anticancer molecules targeting fibroblast growth factor receptors. Trends Pharmacol Sci. 2012, 33(10): 531-541. (IF=11.539) 
22、Gong Q, Wu F, Pan X, Yu J, Li Y, Lu T, Li XK, Lin Z*: Soluble C-X-C chemokine ligand 16 levels are increased in gout patients. Clin Biochem. 2012 , 45(16-17): 1368-73. (IF=2.275) 
23、Wang Z, Zhang H, Xu X, Shi H, Yu X, Wang X, Yan Y, Fu X, Hu H, Li XK, Xiao J*: bFGF inhibits ER stress induced by ischemic oxidative injury via activation of the PI3K/Akt and ERK1/2 pathways. Toxicol Lett. 2012, 212(2): 137-146. (IF=3.262) 
24、Huang Z*, Zhu G, Sun C, Zhang J, Zhang Y, Zhang Y, Ye C, Wang X, Ilghari D, Li XK: A novel solid-phase site-specific PEGylation enhances the in vitro and in vivo biostabilty of recombinant human keratinocyte growth factor 1. PLoS One. 2012, 7(5): e36423. (IF=3.234) 
25、Lin Z, Gong Q, Wu C, Yu J, Lu T, Pan X, Lin S, Li XK*: Dynamic change of serum FGF21 levels in response to glucose challenge in human. J Clin Endocrinol Metab. 2012, 97(7): E1224-1228. (IF=6.209) 
26、Xue W, Liu Y, Zhao J, Cai L, Li XK, Feng W*: Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart. Am J Physiol Heart Circ Physiol. 2012, 302(12): H2528-2535. (IF=3.838) 
27、Ye C, Ilghari D, Niu J, Xie Y, Wang Y, Wang C, Li XK, Liu B, Huang Z*: A comprehensive structure-function analysis shed a new light on molecular mechanism by which a novel smart copolymer, NY-3-1, assists protein refolding. J Biotechnol. 2012, 160(3-4): 169-175. (IF=2.871 )
28、Huang Z, Ye C, Liu Z, Wang X, Chen H, Liu Y, Tang L, Zhao H, Wang J, Feng W*, Li XK*: Solid-phase N-terminus PEGylation of recombinant human fibroblast growth factor 2 on heparin-sepharose column. Bioconjug Chem. 2012, 23(4): 740-750. (IF=4.513)
29、Xiao J, Wang Y, Peng J, Guo L, Hu J, Cao M, Zhang X, Zhang H, Wang Z, Li XK, Yang S, Yang H, Liang G*: A synthetic compound, 1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells. Int J Cancer. 2012, 131(6): 1455-65. (IF=5.085)
30、Liu XJ, Chen YB, Wu XP, Li HY, Jiang C, Tian HS, Tang L, Wang DZ, Yu T*, Li XK: SUMO fusion system facilitates soluble expression and high production of bioactive human fibroblast growth factor 23 (FGF23). Appl Microbiol Biotechnol. 2012, 96: 103–111. (IF=3.337)
31、Zhang C, Lu X, Tan Y, Li B, Miao X, Jin L, Shi X, Zhang X, Miao L, Li XK, Cai L: Diabetes-Induced Hepatic Pathogenic Damage, Inflammation, Oxidative Stress, and Insulin Resistance Was Exacerbated in Zinc Deficient Mouse Model. PLoS One. 2012;7(12): e49257. (IF=3.234)
32、Xing X, Zhang C, Shao M, Tong Q, Zhang G, Li C, Cheng J, Jin S, Ma J, Wang G, Li XK, Cai L: Low-dose radiation activates akt and nrf2 in the kidney of diabetic mice: a potential mechanism to prevent diabetic nephropathy. Oxid Med Cell Longev. 2012: 291087. (IF=3.516 )
33、Wang C, Yu YL, Li QC, Gao SS, Jia XL, Chen XL, Wang RX, Li T, Wang WH, Li XK, Wu XP*: P7 peptides suppress the proliferation of K562 cells induced by basic fibroblast growth factor. Tumor Biology. 2012, 33(4): 1085-1093. (IF=3.611)
34、Wang CY, George B, Chen SL, Feng BA, Li XK, Chakrabarti S: Genotoxic stress and activation of novel DNA repair enzymes in human endothelial cells and in the retinas and kidneys of streptozotocin diabetic rats. Diabetel-metabolism Research and Reviews. 28(4): 329-337. (IF=3.553)
35、Pan Y, Wang Y, Cai L, Cai Y, Hu J, Yu C, Li J, Feng Z, Yang S, Li XK , Liang G*: Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats. British Journal of Pharmacology. 2012,166(3): 1169-1182. (IF=4.842)