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科学研究

科研动态

2013年

时间:2018年04月18日 访问次数:
1、Wang Y, Liu Z, Sun Y, Cai Y, Zhang X, Zhao C, Zhao Y, Wei T, Shen X, Li XK*, Liang G*: Discovery and identification of new non-ATP competitive FGFR1 inhibitors with therapeutic potential on non-small-cell lung cancer. Cancer Lett. 2014, 344(1): 82-9.(IF=5.621)
2、Pan Y, Zhang X, Wang Y, Cai L, Ren L, Tang L, Wang J, Zhao Y, Wang Y, Liu Q, Li XK, Liang G*: Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecules Attenuates Renal Macrophage Infiltration and Injury in Diabetic Mice. PLoS One. 2013, 8(11): e79084. (IF=3.234)
3、Wang Y, Hu J, Cai Y, Xu S, Weng B, Peng K, Wei X, Wei T, Zhou H, Li XK, Liang G*: An Oxygen-Chelate Complex, Palladium Bis-acetylacetonate, Induces Apoptosis in H460 Cells via Endoplasmic Reticulum Stress Pathway Rather than Interacting with DNA. J Med Chem. 2013, 56(23): 9601-11. (IF=5.447)
4、Chen Z, Xie B, Zhu Q, Xia Q, Jiang S, Cao R, Shi L, Qi D, Li XK, Cai L*: FGFR4 and TGF-β1 Expression in Hepatocellular Carcinoma: Correlation with Clinicopathological Features and Prognosis. Int J Med Sci. 2013, 10(13): 1868-75. (IF=2.003)
5、Niu J, Zhu Y, Song L, Xie Y, Zhang Y, Wang H, Li XK, Liu B*, Cai L, Huang Z*: One-Step Production of Bioactive Proteins through Simultaneous PEGylation and Refolding. Bioconjug Chem. 2014, 25(1): 63-71. (IF=4.513)
6、Zhang C, Shao M, Yang H, Chen L, Yu L, Cong W, Tian H, Zhang F, Cheng P, Jin L, Tan Y, Li XK, Cai L*, Lu X*: Attenuation of Hyperlipidemia- and Diabetes-Induced Early-Stage Apoptosis and Late-Stage Renal Dysfunction via Administration of Fibroblast Growth Factor-21 Is Associated with Suppression of Renal Inflammation. PLoS One. 2013, 8(12): e82275. (IF=3.234)
7、Zhang C, Zhang L, Chen S, Feng B, Lu X, Bai Y, Liang G, Tan Y, Shao M, Skibba M, Jin L, Li XK, Chakrabarti S*, Cai L*: The prevention of diabetic cardiomyopathy by non-mitogenic acidic fibroblast growth factor is probably mediated by the suppression of oxidative stress and damage. PLoS One. 2013, 8(12): e82287(IF=3.234)
8、Wu X*, Huang H, Wang C, Lin S, Huang Y, Wang Y, Liang G, Yan Q, Xiao J, Wu J, Yang Y, Li XK: Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation. Oncotarget. 2013, 4(10): 1819-28. (IF=6.359)
9、Liu Z, Sun Y, Ren L, Huang Y, Cai Y, Weng Q, Shen X, Li XK, Liang G*, Wang Y*: Evaluation of a curcumin analog as an anti-cancer agent inducing ER stress-mediated apoptosis in non-small cell lung cancer cells. BMC Cancer. 2013, 13(1): 494. (IF=3.362)
10、Danopoulos S, Parsa S, Al Alam D, Tabatabai R, Baptista S, Tiozzo C, Carraro G, Wheeler M, Barreto G, Braun T, Li XK, Hajihosseini MK, Bellusci S*: Transient Inhibition of FGFR2b-Ligands Signaling Leads to Irreversible Loss of Cellular b-Catenin Organization and Signaling in AER during Mouse Limb Development. PLoS One. 2013, 8(10): e76248. (IF=3.234)
11、Cong WT, Ling J, Tian HS, Ling R, Wang Y, Huang BB, Zhao T, Duan YM, Jin LT*, Li XK: Proteomic study on the protective mechanism of fibroblast growth factor 21 to ischemia-reperfusion injury. Can J Physiol Pharmacol. 2013, 91(11): 973-84. (IF=1.77)
12、Liang G*, Chen G, Wei X, Zhao Y, Li XK: Small molecule inhibition of fibroblast growth factor receptors in cancer. Cytokine Growth Factor Rev. 2013, 24(5): 467-75. (IF=5.357)
13、Wang C, Chang JY, Yang C, Huang Y, Liu J, You P, McKeehan WL, Wang F, Li XK*: Type 1 Fibroblast Growth Factor Receptor in Cranial Neural Crest Cell-derived Mesenchyme Is Required for Palatogenesis. J Biol Chem. 2013, 288(30): 22174-83. (IF=4.573)
14、Li T, Luo W, He D, Wang R, Huang Y, Zeng X, Wang W, Chen X, Gao S, Yu Y, Li XK, Wu X*: A short peptide derived from the gN helix domain of FGF8b suppresses the growth of human prostate cancer cells. Cancer Lett. 2013, 339(2): 226-36. (IF=5.621)
15、Chen H, Huang Z, Dutta K, Blais S, Neubert TA, Li XK, Cowburn D, Traaseth NJ, Mohammadi M*: Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep. 2013, 4(2): 376-84.(IF=8.358)
16、Huang Z, Chen H, Blais S, Neubert TA, Li XK*, Mohammadi M*: Structural Mimicry of A-Loop Tyrosine Phosphorylation by a Pathogenic FGF Receptor 3 Mutation. Structure. 2013, 21(10):1889-1896(IF=5.618)
17、Zhao YZ, Lu CT*, Li XK, Cai J: Ultrasound-mediated strategies in opening brain barriers for drug brain delivery. Expert Opin Drug Deliv. 2013, 10(7): 987-1001.(IF=4.84)
18、Zhang HY, Wang ZG, Wu FZ, Kong XX, Yang J, Lin BB, Zhu SP, Lin L, Gan CS, Fu XB, Li XK, Xu HZ*, Xiao J*: Regulation of Autophagy and Ubiquitinated Protein Accumulation by bFGF Promotes Functional Recovery and Neural Protection in a Rat Model of Spinal Cord Injury. Mol Neurobiol. 2013, 48: 452–464.(IF=5.137)
19、Lin ZF, Tian HS, Karen S.L. Lam, Lin SQ, Ruby C.L. Hoo, Morichika K, Nobuyuki I, Yu W, Stefan R.B, Xu AM and Li XK *: Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice. Cell Metab. 2013, 17(5): 779-89. (IF=17.565)
20、Shi HX, Lin C, Lin BB, Wang ZG, Zhang HY, Wu FZ, Cheng Y, Xiang LJ, Guo DJ, Luo X, Zhang GY, Fu XB, Bellusci S, Li XK*, Xiao J*: The anti-scar effects of basic fibroblast growth factor on the wound repair in vitro and in vivo. PLoS One. 2013, 8(4): e59966. (IF=3.234)
21、Hu J, Wang Y, Wei X, Wu X, Chen G, Cao G, Shen X, Zhang X, Tang Q, Liang G*, Li XK*: Synthesis and biological evaluation of novel thiazolidinone derivatives as potential anti-inflammatory agents. Eur J Med Chem. 2013, 64C: 292-301.(IF=3.447)
22、Song L, Huang Z, Chen Y, Li H, Jiang C*, Li XK*: High-efficiency production of bioactive recombinant human fibroblast growth factor 18 in Escherichia coli and its effects on hair follicle growth. Appl Microbiol Biotechnol. 2014, 98(2): 695-704. (IF=3.337)
23、Wang Y, Wang H, Xia J, Liang T, Wang G, Li XK, Yang YG*: Activated CD8 T cells acquire NK1.1 expression and preferentially locate in the liver in mice after allogeneic hematopoietic cell transplantation. Immunol Lett. 2013, 150(1-2): 75-8. (IF=2.512)
24、Cong W, Ma W, Zhao T, Zhu Z, Wang Y, Tan Y, Li XK, Jin L, Cai L*: Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid-coenzyme A transferase 1 nitration at Trp374. Am J Physiol Endocrinol Metab. 2013, 304(8): E826-35. (IF=3.785)
25、Zhao Y, Tan Y, Xi S, Li Y, Li C, Cui J, Yan X, Li XK, Wang G, Li W*, Cai L*: A novel mechanism by which SDF-1β protects cardiac cells from palmitate-induced ER stress and apoptosis via CXCR7 and AMPK/p38 MAPK-mediated IL-6 generation. Diabetes. 2013. 62(7): 2545-58. (IF=8.095)
26、Wang W, Chen X, Li T, Li Y, Wang R, He D, Luo W, Li XK, Wu X*: Screening a phage display library for a novel FGF8b-binding peptide with anti-tumor effect on prostate cancer. Exp Cell Res. 2013, 319(8): 1156-64. (IF=3.246)
27、Jiang X, Zhang C, Xin Y, Huang Z, Tan Y, Huang Y, Wang Y, Feng W, Li XK, Li W, Qu Y*, Cai L*:Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. Toxicol Lett. 2013, 219(1): 65-76. (IF=3.262)
28、Jiang X, Zhang C, Xin Y, Huang Z, Tan Y, Huang Y, Wang Y, Feng W, Li XK, Li W, Qu Y*, Cai L*:Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. Toxicol Lett. 2013, 219(1): 65-76. (IF=3.262)
29、Zhao YZ, Dai DD, Lu CT, Chen LJ, Lin M, Shen XT, Li XK, Zhang M, Jiang X, Jin RR, Li X, Lv HF, Cai L*, Huang PT: Epirubicin loaded with propylene glycol liposomes significantly overcomes multidrug resistance in breast cancer. Cancer Letters. 2013, 330(1): 74-83. (IF=5.621)
30、Gao HC*, Zhu H, Song CY, Lin L, Xiang Y, Yan ZH, Bai GH, Ye FQ, Li XK: Metabolic Changes Detected by Ex Vivo High Resolution 1H-NMR Spectroscopy in the Striatum of 6-OHDA-Induced Parkinson's Rat. Mol Neurobiol. 2013, 47(1): 123-130. (IF=5.137) 
31、Zhang HY, Zhang X, Wang ZG, Shi HX, Wu FZ, Lin BB, Xu XL, Wang XJ, Fu XB, Li ZY, Shen CJ, Li XK*, Xiao J: Exogenous Basic Fibroblast Growth Factor Inhibits ER Stress-Induced Apoptosis and Improves Recovery from Spinal Cord Injury. CNS Neuroscience & Therapeutics. 2013, 19(1): 20-29. (IF=3.931)
32、Li WJ, Zhou N, Yu Q, Li XK, Yu YQ, Sun SL, Kou CG, Chen DC, Xiu MH, Kosten TR. Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 2013, 612(6): 538-545. (IF=3.416)
33、Zhou N, Yu Q, Li XK, Yu YQ, Kou CG, Li WJ, Xu HQ, Luo XG, Zuo LJ, Kosten TR . Association of the dopamine -hydroxylase 19bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Human Psychopharmacology-Clinical and Experimental. 2013, 28(3): 230-237. (IF=2.192)
34、Abouelmaatti RR, Algammal AM, Li XK, Ma JS, Abdelnaby EA, Elfeil WMK: Cloning and analysis of Nile tilapia Toll-like receptors type-3 mRNA. Centra European Journal of Immunology. 2013, 38(3): 277-282. (IF=0.28)