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科学研究

科研动态

2015年

时间:2018年04月18日 访问次数:
1、Ye L, Yang Y, Zhang X, Cai P, Li R, Chen D, Wei X, Zhang X, Xu H, Xiao J, Li XK*, Lin L*, Zhang HY*: The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals. Int J Mol Sci. 2015. 17(1). (IF 4.509)
2、Huang ZF, Marsiglia WM, Basu Roy U, Rahimi N, Ilghari D, Wang H, Chen H, Gai W, Blais S, Neubert TA, Mansukhani A, Traaseth NJ, Li XK*, Mohammadi M*.Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ. Mol Cell. 2015. 61(1):98-110. (IF 15.2)
3、Zheng H, Zhao LC, Xia H, Xu C, Wang D, Liu K, Lin L, Li XK, Yan ZH*, Gao HC*: NMR-Based Metabolomics Reveal a Recovery from Metabolic Changes in the Striatum of 6-OHDA-Induced Rats Treated with Basic Fibroblast Growth Factor. Mol Neurobiol. 2015. [Epub ahead of print] (IF 5.137)
4、Tian HS, Zhao Y, Chen N, Wu M, Gong W, Zheng J, Fernig DG, Jungbauer A, Wang D, Li XK*, Jiang C*: High production in E. coli of biologically active recombinant human fibroblast growth factor 20 and its neuroprotective effects. Appl Microbiol Biotechnol. 2015. [Epub ahead of print] (IF 3.337)
5、Zhao HY, Wu J, Zhu JJ, Xiao ZC, He CC, Shi HX, Li XK, Yang SL*, Xiao J*: Research Advances in Tissue Engineering Materials for Sustained Release of Growth Factors. Biomed Res Int. 2015, 2015: 808202. (IF 1.579)
6、Li W, Du X, Chen Q, Kang Y, Xu C, Fan L, Ye H, Ying S, Shi L, Jin R*, Wu J, Liang G, Li XK: Peptidomimetic suppresses proliferation and invasion of gastric cancer cells by fibroblast growth factor 2 signaling cascade blockage. Anticancer Drugs. 2015. (IF 1.784)
7、Liu X, Dong Y, Yao N, Zhang Y, Wang N, Cui X, Li X, Wang Y, Wang F, Yang J, Guan L, Du L, Li H, Li XK*: De Novo Sequencing and Analysis of the Safflower Transcriptome to Discover Putative Genes Associated with Safflor Yellow in Carthamus tinctorius L. Int J Mol Sci. 2015, 16(10): 25657-77. (IF 2.862)
8、Huang J, Yang J, Guan L, Yi S, Du L, Tian H, Guo Y, Zhai F, Lu Z, Li H, Li XK*, Jiang C*: Expression of bioactive recombinant human fibroblast growth factor 10 in Carthamus tinctorius L.seeds. Protein Expr Purif. 2015, pii: S1046-5928(15)30066-8. (IF 1.695)
9、Zhao HY, Wu J, Zhu JJ, Xiao ZC, He CC, Shi HX, Li XK, Yang SL*, Xiao J*: Research Advances in Tissue Engineering Materials for Sustained Release of Growth Factors. Biomed Res Int. 2015, 2015: 808202. (IF 1.579)
10、Zhu SP, Wang ZG, Zhao YZ, Wu J, Shi HX, Ye LB, Wu FZ, Cheng Y, Zhang HY, He S, Wei X, Fu XB, Li XK, Xu HZ*, Xiao J*: Gelatin Nanostructured Lipid Carriers Incorporating Nerve Growth Factor Inhibit Endoplasmic Reticulum Stress-Induced Apoptosis and Improve Recovery in Spinal Cord Injury. Mol Neurobiol. 2015. [Epub ahead of print] (IF 5.137)
11、Singh SK, Chen NM, Hessmann E, Siveke J, Lahmann M, Singh G, Voelker N, Vogt S, Esposito I, Schmidt A, Brendel C, Stiewe T, Gaedcke J, Mernberger M*, Crawford HC, Bamlet WR, Zhang JS, Li XK, Smyrk TC, Billadeau DD, Hebrok M, Neesse A, Koenig A, Ellenrieder V. Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity. EMBO J. 2015, 34(4):517-30. (IF 10.434)
12、Zhang F, Yu L, Lin X, Cheng P, He L, Li XK, Lu X, Tan Y, Yang H, Cai L*, Zhang C*: Minireview: Roles of fibroblast growth factors 19 and 21 in metabolic regulation and chronic diseases. Mol Endocrinol. 2015, 29(10): 1400-13 (IF 4.022)
13、Yi S, Yang J, Huang J, Guan L, Du L, Guo Y, Zhai F, Wang Y, Lu Z, Wang L, Li H, Li XK*, Jiang C*: Expression of bioactive recombinant human fibroblast growth factor 9 in oil bodies of Arabidopsis thaliana. Protein Expr Purif. 2015, 116: 127-32. (IF 1.695)
14、Zheng L, Hui Q, Tang L, Zheng LL, Jin Z, Yu BJ, Wang ZT, Lin P, Yu WD, Li HY*, Li XK*, Wang XJ*: TAT-Mediated Acidic Fibroblast Growth Factor Delivery to the Dermis Improves Wound Healing of Deep Skin Tissue in Rat. PLoS One. 2015, 10(8): e0135291. (IF 3.234)
15、Zhao C, Liu Y, Xiao J, Liu L, Chen S, Mohammadi M, McClain CJ, Li XK*, Feng WK*: FGF21 Mediates Alcohol-Induced Adipose Tissue Lipolysis by Activation of Systemic Release of Catecholamine in Mice. J Lipid Res. 2015, 56(8): 1481-91. (IF=4.421)
16、Shi H, Cheng Y, Ye J, Cai P, Zhang J, Li R, Yang Y, Wang Z, Zhang H, Lin C, Lu X, Jiang L, Hu A, Zhu X, Zeng Q, Fu X, Li XK*, Xiao J*: bFGF Promotes the Migration of Human Dermal Fibroblasts under Diabetic Conditions through Reactive Oxygen Species Production via the PI3K/Akt-Rac1- JNK Pathways. Int J Biol Sci. 2015, 11(7): 845-59. (IF=4.509)
17、Yan X, Chen J, Zhang C, Zeng J, Zhou S, Zhang Z, Lu X, Chen J, Feng W, Li XK, Tan Y*: Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice. Cardiovasc Diabetol. 2015, 14(1): 77.(IF=4.015)
18、Cheng Y, Zhang J, Deng L, Johnson NR, Yu X, Zhang N, Lou T, Zhang Y, Wei X, Chen Z, He S, Li XK*, Xiao J*: Intravenously delivered neural stem cells migrate into ischemic brain, differentiate and improve functional recovery after transient ischemic stroke in adult rats. Int J Clin Exp Pathol. 2015, 8(3): 2928-36.(IF=1.891)
19、Zhang C, Huang Z, Gu J, Yan X, Lu X, Zhou S, Wang S, Shao M, Zhang F, Cheng P, Feng W, Tan Y*, Li XK*: Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway. Diabetologia. 2015, 58(8): 1937-48. (IF=6.671)
20、Cai J, Dou G, Zheng L, Yang T, Jia X, Tang L, Huang Y, Wu WC*, Li XK, Wang X: Pharmacokinetics of topically applied recombinant human keratinocyte growth factor-2 in alkali-burned and intact rabbit eye. Exp Eye Res. 2015, 136: 93-9.(IF=2.709)
21、Shao ML, Yu LC, Zhang FF, Lu XM, Li XK, Cheng P, Lin XF, He LQ, Jin SZ, Tan Y, Yang H, Zhang C, Cai L*: Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model. Am J Physiol Endocrinol Metab. 2015, 309(1): E45-54. (IF=3.785)
22、Wang DZ, Ma JS, Sun DF, Li HY, Jiang C*, Li XK*: Expression of bioactive anti-CD20 antibody fragments and induction of ER stress response in Arabidopsis seeds. Appl Microbiol Biotechnol. 2015. 99(16): 6753-64. (IF=3.337)
23、Fan L, Li WL, Ying SL, Shi LY, Wang Z, Chen GZ, Ye H, Wu XP*, Wu JZ*, Liang G, Li XK: A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer. Tumour Biol. 2015 , 36(9): 7233-41.(IF=3.661)
24、Yang J, Guan Ll, Guo YX, Du LN, Wang FW, Wang YF, Zhen L, Wang QM, Zou DY, Chen W, Yu L*, Li HY*, Li XK*: Expression of biologically recombinant human acidic fibroblast growth factor in Arabidopsis thaliana seeds via oleosin fusion technology. Gene. 2015, 566(1): 89-94. (IF=2.138)
25、Wu JZ, Wei T, Tang QQ, Weng BX, Li WL, Jiang X, Ding T, Li XK, Liang G, Cai YP*, Ji JS*: Discovery and anti-cancer evaluation of two novel non-ATP-competitive FGFR1 inhibitors in non-small-cell lung cancer. BMC Cancer. 2015, 15(1): 276. (IF=3.362)
26、Yan XQ, Chen J, Zhang C, Zhou SS, Zhang ZG, Chen J, Feng WK, Li XK, Tan Y*: FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation. J Cell Mol Med. 2015. 19(7): 1557-68. (IF=4.014)
27、MacKenzie B, Henneke I, Hezel S, Al Alam D, El Agha E, Chao CM, Quantius J, Wilhelm J, Jones M, Goth K, Li XK, Seeger W, K?nigshoff M, Herold S, Rizvanov AA, Günther A, Bellusci S: Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair. Am J Physiol Lung Cell Mol Physiol. 2015, 308(10): L1014-24. (IF=4.08)
28、Xu CC, Li WL, Qiu PH, Xia YQ, Du XJ, Wang F, Shen LL, Chen QX, Zhao YJ, Jin R, Wu JZ, Liang G and Li XK: The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. Anti-cancer Drugs. 2015, 26(4): 379-87. (IF=1.784)
29、Lin WH, Xiang LJ, Shi HX, Zhang J, Jiang LP, Cai PT, Lin ZL, Lin BB, Huang Y, Zhang HL, Fu XB, Guo DJ, Li XK, Wang XJ*, Xiao J*: Fibroblast growth factors stimulate hair growth through β-catenin and Shh expression in C57BL/6 mice. Biomed Res Int. 2015, 2015: 730139. (IF=1.579)
30、Xiao J, Wang YD, Bellusci S, Li XK*: Pharmacological application of growth factors: basic and clinical. Biomed Res Int. 2015, 2015: 141794. (IF=1.579)
31、Huang ZF, Tan L, Wang HY, Liu Y, Blais S, Deng JJ, Neubert TA, Gray NS, Li XK*, Mohammadi M*: DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors. ACS Chem Biol. 2015, 10(1): 299-309. (IF=5.331)
32、Lin ZF, Pan XB, Wu F, Ye DW, Zhang Y, Wang Y, Jin LG, Lian QZ, Huang Y, Ding H, Triggle C, Wang K, Li XK*, Xu AM*: Fibroblast Growth Factor 21 Prevents Atherosclerosis by Suppression of Hepatic Sterol Regulatory Element-Binding Protein-2 and Induction of Adiponectin in Mice. Circulation. 2015, 131(21): 1861-71. (IF=14.43)
33、Qian YY, Zhong P, Liang DD, Xu Z, Skibba M, Zeng CL, Li XK, Wei TM, Wu LP, Liang G*: A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats. PLoS One. 2015, 10(3): e0120215. (IF=3.234)
34、Liang DD, Zhong P, Hu J, Lin F, Qian YY, Xu Z, Wang JY, Zeng CL, Li XK, Liang G*: EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse model. J Mol Cell Cardiol. 2015, 82: 63-74. (IF=4.655)
35、Zhao HY, Zhao CQ, Dong YY, Zhang M, Wang YH, Li FY, Li XK, McClain C, Yang SL*, Feng WK*: Inhibition of miR122a by Lactobacillus rhamnosus GG culture supernatant increases intestinal occludin expression and protects mice from alcoholic liver disease. Toxicol Lett. 2015, 234(3): 194-200. (IF=3.262)
36、Jia XC, Tian HS, Tang L, Zheng LL, Zheng L, Yang T, Yu BJ, Wang ZT, Lin P, Li XK*, Wang XJ*: High-Efficiency Expression of TAT-bFGF Fusion Protein in Escherichia coli and the Effect on Hypertrophic Scar Tissue. PLoS One. 2015, 10(2): e0117448. (IF=3.234)
37、Wang ZG, Wang Y, Ye JM, Lu XH, Cheng Y, Xiang LJ, Chen L, Feng WK, Shi HX, Yu XC, Lin L, Zhang HY, Xiao J*, Li XK*: bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway. J Cell Mol Med. 2015, 19(3): 595-607. (IF=4.014)
38、Huang T, Lin XM, Li QC, Luo W, Song L, Tan XP, Wang WH, Li XK, Wu XP*: Selection of a novel FGF23-binding peptide antagonizing the inhibitory effect of FGF23 on phosphate uptake. Appl Microbiol Biotechnol. 2015, 99(7): 3169-77. (IF=3.337)
39、Guo CM, Kaneko S, Sun Y, Huang YC, Vlodavsky I, Li XK, Li ZR*, Li X*: A mouse model of urofacial syndrome with dysfunctional urination. Hum Mol Genet. 2015, 24(7): 1991-9. (IF=6.393)